The FDA is said to have as of late instituted a crack down on weight loss supplements as a result of really serious uncomfortable side effects and even death linked to some dietary supplements such as ephedra. The ban on ephedra items resulted to the creation of so-called ephedra free weight loss supplements, these too are said to yield their fair share of conditions and they too may very well be most likely going to exactly the same fate as ephedra.

These ephedra free medicines are said to result in a boost in heartbeat and a some other side effects on healthy men and women as outlined by a health professional connoisseur who was in the research program.

The inquiry done through the University of California at Berkeley was the first one to research the health effects of reformulated weight loss supplements. Some of the things investigated for included hypertension and pulse rate of volunteers who were given reformulated weight loss supplements made from extracts of bitter orange.

Because of the ban slapped on ephedra by FDA, an increasing sum of body fat loss product manufactures have converted to extracts of bitter orange. The USB study required 20 healthy volunteers, who were given single doses of a weight loss supplement or a placebo.

The diet supplements used in the research program were Xenadrine EFX and Advantra Z, each of which possesses bitter orange extracts. The applied drug was shown to cause a slight increase in heart pulse rate as high as 16 beats in one minute. The Thermogenic Xenadrine EFX for example was shown to rev up heart rate by 13 per cent, a thing that makes it almost equivalent in performance to ephedra.

Bitter orange extracts include synephrine, a component present in over 90% of citrus fruits but found in increased concentrations in fruits such as Sour orange, Zhi shi and bitter orange and which is popularly used as a remedy in the treatment of respiratory tract congestion and blood pressure. Xenadrine EFX features a stimulant in the element, usually caffeine. The quantity of caffeine is Xenadrine is approximated to be the equivalent of 3 coffee cups. This is the element responsible for the rise in blood pressure and people using this product are informed against over dosage.